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Sherrel Howard Drugs of Abuse. Pharmacology and Molecular Mechanisms


Drug abuse has been, and continues to be, a global societal issue with diverse sets of impacts. Drugs of Abuse: Pharmacology and Molecular Mechanisms introduces the basic principles of pharmacology and neuroscience of drug abuse. Understanding the chemistry of commonly abused drugs and their impact on brain function will provide students and researchers with a more profound understanding of the molecular basis of drug abuse and addiction. Drugs of Abuse: Pharmacology and Molecular Mechanisms opens with a brief history of drug use and abuse. Subsequent sections look at specific families of drugs, including stimulants, depressants, and hallucinogens among others, and explore how their chemical make-up interacts with brain function. The final chapter provides a brief overview of clinical substance abuse treatment. Providing a concise, accessible introductory overview of the topic, Drugs of Abuse: Pharmacology and Molecular Mechanisms will be a valuable resource for students, researchers, and others interested in how drugs interact with the brain. Introduces readers to the basic principles of neuroscience and pharmacology as related to drug use and abuse. Explores how the chemical make-up of drugs interact with the brain and can lead to addiction Includes coverage of a wide array of commonly abused families of drugs, including stimulants, depressants, hallucinogens, and others. Provides an essential introduction to the chemical and molecular underpinnings of drug use and abuse

7340.34 RUR

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Группа авторов The Handbook of Drugs and Society


This handbook provides a comprehensive examination of the past and present roles of drugs in society with a focus on theory, research, policy, and practice. Includes 28 original chapters with multi-disciplinary and international perspectives by top social and behavioral scientists Reviews current knowledge in the field, including key research findings, theoretical developments, and methodological debates Identifies ongoing controversies in the field, emergent topics, and areas in need of further inquiry Discusses individual drugs as well as topics like physiological theories of drug use and abuse, public health implications of drugs, patterns of drugs and crime, international drug trade and trafficking, and designer drugs

17310.72 RUR

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Wilfried M. A. Niessen Interpretation of MS-MS Mass Spectra Drugs and Pesticides


Provides comprehensive coverage of the interpretation of LC–MS–MS mass spectra of 1300 drugs and pesticides Provides a general discussion on the fragmentation of even-electron ions (protonated and deprotonated molecules) in both positive-ion and negative-ion modes This is the reference book for the interpretation of MS–MS mass spectra of small organic molecules Covers related therapeutic classes of compounds such as drugs for cardiovascular diseases, psychotropic compounds, drugs of abuse and designer drugs, antimicrobials, among many others Covers general fragmentation rule as well as specific fragmentation pathways for many chemical functional groups Gives an introduction to MS technology, mass spectral terminology, information contained in mass spectra, and to the identification strategies used for different types of unknowns

11996.64 RUR

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Christopher J. Correia College Student Alcohol Abuse


Essential evidence-based strategies for the prevention and reduction of alcohol abuse among college students With contributions from notable substance abuse researchers, this practical guide presents clear strategies for prevention of and interventions for alcohol abuse in the college-age population. Ranging from community-based prevention programs to individual, motivational, and interview-based approaches, College Student Alcohol Abuse explores: The leading theories used to conceptualize college student drinking and related problems, with an emphasis on the clinical implications of each perspective Epidemiology of student drug use—including illicit drugs and nonmedical use of prescription drugs The spectrum of empirically supported prevention programs with a focus on best practices and materials How to conduct assessments and create intervention programs for students with substance abuse problems A must-have resource for every college administrator, resident staff member, and addiction counselor who works with this unique population, College Student Alcohol Abuse translates the latest research findings and interventions into clear and evidence-based strategies for assessing and treating college students who are abusing alcohol.

4355.15 RUR

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Donald Barceloux G. Medical Toxicology of Drug Abuse. Synthesized Chemicals and Psychoactive Plants


This book provides a broad reference covering important drugs of abuse including amphetamines, opiates, and steroids. It also covers psychoactive plants such as caffeine, peyote, and psilocybin. It provides chemical structures, analytical methods, clinical features, and treatments of these drugs of abuse, serving as a highly useful, in-depth supplement to a general medical toxicology book. The style allows for the easy application of the contents to searchable databases and other electronic products, making this an essential resource for practitioners in medical toxicology, industrial hygiene, occupational medicine, pharmaceuticals, environmental organizations, pathology, and related fields.

18844.18 RUR

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Paula Mallea The War on Drugs


A criminal prosecutor discusses the illegal drug trade and the failure of the so-called “War on Drugs” to stop it. In 1971, President Richard Nixon coined the term “War on Drugs.” His campaign to eradicate illegal drug use was picked up by the media and championed by succeeding presidents, including Reagan. Canada was a willing ally in this “war,” and is currently cracking down on drug offences at a time when even the U.S. is beginning to climb down from its reliance on incarceration. Elsewhere in the world, there has been a sea change. The Global Commission on Drug Policy, including international luminaries like Kofi Annan, declared that the War on Drugs “has not, and cannot, be won.” Former heads of state and drug warriors have come out in favour of this perspective. Former presidents Jimmy Carter and Bill Clinton agree with legions of public health officials, scientists, politicians, and police officers that a new approach is essential. Paula Mallea, in The War on Drugs , approaches this issue from a variety of points of view, offering insight into the history of drug use and abuse in the twentieth century; the pharmacology of illegal drugs; the economy of the illegal drug trade; and the complete lack of success that the war on drugs has had on drug cartels and the drug supply. She also looks ahead and discusses what can and is being done in Canada, the U.S., and the rest of the world to move on from the “war” and find better ways to address the issue of illegal drugs and their distribution, use, and abuse.

665.03 RUR

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Glenn Goree A Trilogy of Healing


Broken bones mend. Flesh wounds heal. But where is the emergency room we can rush to when our hearts are broken? Divorce, adultery, spousal abuse, childhood sexual abuse, and addiction to alcohol, drugs, or pornography tear deep, gaping holes in the most tender of organs. There's no bandage and no surgery that will heal these wounds of the soul. However, forgiveness, mercy, and grace become a soothing balm in restoration. Whether you are the victim of a broken heart or the perpetrator of the harm, these poems will assist in your spiritual healing.

813.72 RUR

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Giorgio Minotti Cardiotoxicity of Non-Cardiovascular Drugs


Some drugs which are not aimed at treating heart disease have nevertheless been found to have profound effects on heart muscle. Cardiotoxicity is one of the major forms of toxicity seen in drugs and it accounts for most drug recalls and delays experienced in regulatory approvals.In recent years a number of non-cardiac blockbuster drugs such as terfenadine have been withdrawn from major markets because of cardiotoxicity concerns, while other drugs have either been withdrawn prior to marketing or required labelling changes that significantly restricted their use. In Cardiotoxicity of Non-Cardiovascular Drugs international experts describe the molecular mechanisms and clinical read-outs of cardiac events induced by a broad variety of noncardiovascular drugs. Particular emphasis is paid to the preclinical screening of drug cardiotoxicity. Topics include: metabolic targets of cardiotoxicity regulatory aspects translating molecular mechanisms into clinical trials structure-activity relationships in arrhythmias by antihistamines and psychoactive drugs cardiovascular toxicity of antitumor drugs cardiovascular toxicities of non-steroidal anti-inflammatory drugs cardiovascular toxicities of antiretroviral therapies Cardiotoxicity of Non-Cardiovascular Drugs is an essential guide to this important area of drug development. It will find a place on the bookshelves of researchers, regulators and students in medicinal chemistry, drug development, pharmacology, pharmacy and cardiovascular disease.

15574.44 RUR

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Anna Howard Shaw The Story of a Pioneer: Autobiography

Leslie A King The Misuse of Drugs Act


In recent years, the use of illegal substances has increased, particularly 'designer' drugs which have rapidly become part of youth culture. The need for all involved in drug control to have up to date information about the subject has never been greater. This book helps meet this need by providing a chemical background to the legal controls on drugs of abuse. Although focussed on the UK, some of the provisions of the Misuse of Drugs Act derive from international treaties; the discussion of technical aspects is therefore of wider relevance. Apart from the Act itself, the book also deals with certain aspects of the Misuse of Drugs Regulations. There is detailed coverage of 'designer drugs' and the generic legislation that was introduced to tackle them. The more recent addition of 35 'Ecstasy'-like substances is covered in depth. The significance to the legislation of terms such as salt, base, stereoisomer, ester, ether, derivative, homologue and isotope are described, and the text is supplemented by 23 Tables and over 80 chemical structures. There are eleven Appendices covering topics such as precursor chemicals, related legislation, stated cases, sentencing guidelines and the chemical characteristics of commonly-abused drugs. Up-to-date lists of controlled drugs, with cross references to their status in UN treaties, are provided and a number of pending and other possible changes to the Act are included together with a guide to nomenclature and synonyms. Although primarily aimed at forensic scientists, this book will be of great benefit to all bodies concerned with drug control, including the police, customs officers, lawyers and government departments.

3023.45 RUR

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Randell Alexander, MD, PhD Child Abuse Pocket Atlas, Volume 2


212 pages, 445 images, 11 contributors
Sexual abuse of children is an especially delicate matter, and each reported case should be treated with exacting care. Accurate identification and appropriate response to symptoms of sexual maltreatment in children is essential to the resilient, long-term recovery of survivors. Therefore, it is incumbent upon those professionals who care for and represent the interests of survivors to recognize cases of childhood sexual abuse and to respond expediently, in the survivors’ best interest.
Child Abuse Pocket Atlas Series, Volume 2: Sexual Abuse, the second addition to an ongoing series on child abuse, will support medical practitioners and other affiliated sexual assault response providers in identifying and interpreting the physical signs and symptoms of sexual abuse in children.

4792.53 RUR

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Howard Pyle Pyle's Book of Pirates

Peter Stafford Psychedelics Encyclopedia


Traces the history of the use of hallucinogenic drugs and discusses the psychological and physical effects of LSD, marijuana, mescaline, and other drugs.

2580.25 RUR

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Sally Robinson Preventing the Emotional Abuse and Neglect of People with Intellectual Disability


There's so many different types of abuse, and it all comes down to the same thing. It's making people nothing. And Fran was nothing. There was never anything nice said about her, everything was negative. And she had to put up with that, and we had to put up with that, until we all sort of believed it, almost.' Preventing the Emotional Abuse and Neglect of People with Intellectual Disability throws light onto the traumatic experiences faced by people with intellectual disability living in disability accommodation services. Through the narratives of nine people with intellectual disability and their family members, it reveals: the problem of systematic abuse; the cumulative impact of emotional and psychological abuse and neglect over time; recognition of the abuse by people with intellectual disability; and the lack of moral authority afforded to them in abuse acknowledgement and reporting. The author suggests a number of positive approaches and methods to help all those working with people with intellectual disability to prevent emotional abuse, respond appropriately and effectively support the recovery of victims. This book will prove to be indispensable for social care workers, care home managers, social workers, researchers and academics in the disability field, social sciences students, human rights workers and abuse practitioners.

2429.82 RUR

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Robyn MacBridge Sexual Abuse - Child True Stories


"Sexual Abuse – Child Sexual Abuse True Stories (What You Need to Know & Shocking Child Abuse Statistics!)" is more than just a book of child abuse stories. The victims of child sexual abuse are 1 out of 4 girls and 1 out of 7 boys (World Health Organization). A majority of the offenders are people they know and trust like their family members. Each child has his/her own childhood sexual abuse story and it's a horror that each one have had to live through. There are 7 brief child abuse stories in this book that allows you to take a peek into their world to see what the child experienced, as well as food for thought about that particular experience. In an effort to increase awareness and keep the frequency of sexual abuse and child molestation to a minimum, this book also includes advice from experts and practical tips – some of which might have never crossed your mind, as well as a look into the plight of survivors. The child sexual abuse statistics alone are heartbreaking and unbelievable; things that are hard to fathom, and so many. You'll also find out why mothers who know about it many times do nothing about it and what that does to the child on into adulthood. If you've wondered what child sexual abuse is about – not only the stories – but its prevalence (statistics), psychological and emotional impact, things that can be done to help prevent it, and available resources on a worldwide basis including current phone numbers, support groups and websites, all of that information is contained in this book. Collectively with just a little awareness about that dark world, I feel we can make a difference in protecting the innocence of children/adolescence/teens from molestation and sexual abuse.

295.16 RUR

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Anzenbacher Pavel Metabolism of Drugs and Other Xenobiotics


A practice-oriented desktop reference for medical professionals, toxicologists and pharmaceutical researchers, this handbook provides systematic coverage of the metabolic pathways of all major classes of xenobiotics in the human body. The first part comprehensively reviews the main enzyme systems involved in biotransformation and how they are orchestrated in the body, while parts two to four cover the three main classes of xenobiotics: drugs, natural products, environmental pollutants. The part on drugs includes more than 300 substances from five major therapeutic groups (central nervous system, cardiovascular system, cancer, infection, and pain) as well as most drugs of abuse including nicotine, alcohol and «designer» drugs. Selected, well-documented case studies from the most important xenobiotics classes illustrate general principles of metabolism, making this equally useful for teaching courses on pharmacology, drug metabolism or molecular toxicology. Of particular interest, and unique to this volume is the inclusion of a wide range of additional xenobiotic compounds, including food supplements, herbal preparations, and agrochemicals.

21945.8 RUR

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Robert E. Howard 80+ ADVENTURE TALES OF ROBERT HOWARD - The Ultimate Action-Packed Collection

Paris Goodyear-Brown Handbook of Child Sexual Abuse. Identification, Assessment, and Treatment


A comprehensive guide to the identification, assessment, and treatment of child sexual abuse The field of child sexual abuse has experienced an explosion of research, literature, and enhanced treatment methods over the last thirty years. Representing the latest refinements of thought in this field, Handbook of Child Sexual Abuse: Identification, Assessment, and Treatment combines the most current research with a wealth of clinical experience. The contributing authors, many of whom are pioneers in their respective specialties, include researchers and clinicians, forensic interviewers and law enforcement professionals, caseworkers and victim advocates, all of whom do the work of helping children who have been sexually victimized. Offering a snapshot of the state of the field as it stands today, Handbook of Child Sexual Abuse explores a variety of issues related to child sexual abuse, from identification, assessment, and treatment methods to models for implementation and prevention, including: The impact of sexual abuse on the developing brain The potential implications of early sexual victimization Navigating the complexities of multidisciplinary teams Forensic interviewing and clinical assessment Treatment options for children who have traumagenic symptoms as a response to their sexual victimization Treating children with sexual behavior problems and adolescents who engage in illegal sexual behavior Secondary trauma and vicarious traumatization Cultural considerations and prevention efforts Edited by a leader in the field of child therapy, this important reference equips helping professionals on the front lines in the battle against child sexual abuse—not merely with state-of-the-art knowledge—but also with a renewed vision for the importance of their role in the shaping of our culture and the healing of victimized children.

7521.75 RUR

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Sheryl St. Germain 50 Miles


• Opiate overdoses are the leading cause of accidental deaths among those under 50. • Memoirs about substance abuse are overwhelmingly about recovery. It is the rare memoir that ends in death. • There are many books about recovery but there are no literary books that the author knows of that addresses what it is like to lose a family member or other to drugs. • No memoirs or scientific books discuss the possibility of later drug abuse related to the prescribing of Ritalin or Adderall for ADHD. • It includes, as a secondary aspect, the recovery of the mother and her methods of coping and grieving the loss of her son. Video games feature prominently in the longest essay in the book, as a form of connection and solace.

739.01 RUR

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Randell Alexander, MD, PhD Child Abuse Pocket Atlas, Volume 4


250 pages, 505 images, 12 contributors
In the investigation of child abuse, consistent investigative protocol and clear, thorough documentation of facts and findings are essential to ensuring justice for victims, both for those who survive and for those who do not. In order to achieve the best possible results in such cases, multidisciplinary investigative teams of first responders, law enforcement, and medical practitioners should be well prepared for the process of investigation and documentation as they work in tandem toward a just end for every case of abuse.
Readers in medicine, law enforcement, and any other readers involved with child abuse and death investigations will enjoy the benefit of Child Abuse Pocket Atlas Series, Volume 4: Investigation, Documentation, and Radiology, a compact and accessible guide to investigation and documentation.

4792.53 RUR

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Группа авторов Chiral Drugs


An integrated view of chiral drugs—from concept and synthesisto pharmaceutical properties Chirality greatly influences a drug's biological and pharmacological properties. In an effort to achieve more predictable results from chiral drugs, the Food and Drug Administration now requires that these medicines be as pure as possible, which places great demands on drug synthesis, purification, analysis, and testing. To assist researchers in acquiring the essential knowledge to meet these rigid guidelines, Chiral Drugs focuses on three vital chiral technologies—asymmetric synthesis, biocatalytic process, and chiral resolution—to offer details on the basic concepts, key developments, and recent trends in chiral drug discovery, along with: The history of chiral drugs development and industrial applications of chiral technologies A section listing twenty-five approved or advanced-trial chiral drugs that lists each drug name, chemical name and properties, a representative synthetic pathway, pharmacological characterizations, and references An interdisciplinary approach combining synthetic organic chemistry, medicinal chemistry, and pharmacology Nearly two-thirds of the drugs on today's market are chiral drugs. Reducing and eliminating their negative characteristics is an ongoing and serious challenge for the pharmaceutical industry. With its well-balanced approach to covering each important aspect of chirality, Chiral Drugs champions important strategies for tipping the medical scale in a positive direction for the production of more effective—and safer—drugs.

15183.09 RUR

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Suzan Collins Safeguarding Adults


Working in residential or domiciliary settings involves a responsibility to safeguard adults from harm and abuse. This workbook will provide staff and relatives with the ability to make sensible choices concerning prevention and protection, as well as responding to and reporting concerns. Safeguarding Adults examines the different forms of abuse, where abuse can take place and how and where to report the suspected abuse. The workbook meets the requirements of care standards and promotes best practice by enabling staff to feel confident contributing to keeping the people they support safe from harm and abuse. Designed to meet the requirements of Health and Social Care (Adults) NVQ Level 3, Unit 35, this workbook is also a valuable source of guidance for any social care worker wanting or needing to improve their practice in relation to safeguarding adults from harm and abuse.

2061.11 RUR

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